Atacand tab B
Manufacturer
AstraZeneca
Distributor
Zuellig Pharma
Contents
Candesartan cilexetil
MIMS Class
Angiotensin II
Antagonists
Indications
Treatment of
hypertension.
Dosage
Adult 8-16 mg
once daily. Patients w/ severe renal or hepatic impairment: Start w/ 4
mg once daily.
Contraindication
Pregnancy,
lactation.
Precautions
Patients w/
bilateral renal artery stenosis or stenosis of the artery to a solitary
kidney. Correct intravascular vol status
prior to treatment. Concomitant administration w/ K-sparing
diuretics. Perform periodic monitoring of serum K & creatinine levels in patients w/ severe renal dysfunction.
Patients suffering from haemodynamically relevant aortic or mitral valve stenosis or
obstructive hypertrophic cardiomyopathy.
Adverse Reactions
Back
pain. Very rarely: Leukopenia, neutropenia & agranulocytosis,
hyperkalaemia, hyponatraemia, increased liver enzymes, abnormal hepatic
function or hepatitis, angioedema, rash, urticaria, pruritus, renal
impairment, including renal failure in susceptible patients.
Drug Interaction
K-sparing diuretics, K supplements, salt substitutes
containing K or other drugs that may increase K levels, lithium, other antihypertensives.
Packing/Presentation
Tablet
8mg x 28's
16mg x 28's
Pregnancy Category
C; D in 2nd &
3rd trimesters.