Lipitor film-coated tab    B   

Manufacturer 

Pfizer

Distributor 

Zuellig Pharma

Contents

Atorvastatin Ca 

MIMS Class

Antihyperlipidaemic Agents 

Indications    

Reduction of elevated total & LDL cholesterol, apolipoprotein B & triglycerides & to increase HDL-cholesterol in patients w/ primary hypercholesterolaemia, combined hyperlipidaemia, heterozygous & homozygous familial hypercholesterolaemia. 

Dosage  

Dose range: 10-80 mg once daily. Starting & maintenance dose should be individualised according to LDL-cholesterol levels, the goal of therapy & patient response. 

Contraindication   

Active liver disease or elevated serum transaminases > 3 times the upper limit of normal. Pregnancy & lactation. 

Precautions    

Monitor for creatine phosphokinase & transaminase elevations. Avoid alcohol consumption. 

Adverse Reactions  

GI disturbances, headache, myalgia, asthenia, insomnia, angioneurotic edema, muscle cramps, myositis, myopathy, cholestatic jaundice, peripheral neuropathy, pruritus. 

Drug Interaction  

Risk of myopathy increased w/ concurrent administration of cyclosporin, fibric acid derivatives, erythromycin, niacin or azole antifungals. Decreased atorvastatin plasma conc w/ oral antacid suspensions containing Mg & Al hydroxides, & colestipol. Increases steady-state plasma digoxin conc. Increased atorvastatin plasma conc w/ erythromycin. Increases AUC values for norethindrone & ethinylestradiol. 

Packing/Presentation  

film-coated tablet

10mg x 30's  

20mg x 30's  

40mg x 30's

80mg x 30's

Pregnancy Category

X